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Weight Loss and Medical News November 10th, 2008
Caution Advised With Nonprescription Weight Loss Pills
Over-the-counter weight-loss pills are no quick fix to melt away extra pounds. Many local drugstores sell diet pills, and even more choices are available on the Internet. But most diet pills haven’t been proved safe or effective, and some are downright dangerous, according to a special report in the November issue of Mayo Clinic Women’s HealthSource.
The report looks at popular weight-loss diets, eating plans and strategies, including diet pills.
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Tesofensine: New Miracle Weight Loss Drug?
Weight loss drugs have been something of a flop. Between Acomplia being ordered off the shelves for making people mad, and the lackluster performance of the other popular weight loss drugs - there hasn’t been much to celebrate for the pharmaceutical companies *cue crocodile tears.
That is until now… maybe.
An experimental drug called tesofensine is said to produce double the weight loss of current diet drugs. The drug works on three different appetite regulatory centers of the brain - the neurotransmitters noradrenaline, dopamine, and serotonin.
The phase II study, reported in The Lancet, included 203 obese patients whose average weight was about 220 pounds.
The average weight loss was 28 pounds in the highest dose of tesofensine compared to the placebo group which lost an average of 5 pounds. Sounds great…until you read the squinty print:
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Weight-Loss Pills Lead to Positive Tests
A significant number of NFL players have tested positive under the league’s steroid policy because of their use of weight-loss pills containing a substance banned by the league, sources familiar with the cases said yesterday.
A Denver television station, KDVR-TV, reported six to 10 players tested positive, including tailback Deuce McAllister and defensive end Will Smith of the New Orleans Saints. One to two other Saints players also tested positive, according to the report, which cited an NFL source.
Most of the players, including McAllister and Smith, tested positive for bumetanide, described as a drug used to treat fluid retention. The diuretic reportedly also can be used as a steroid-masking agent and is on the NFL’s list of banned substances. According to the report, bumetanide belongs to a group of medicines called loop diuretics, or water pills.
Sources familiar with the case confirmed the report. The players are subject to possible suspensions, pending appeals.
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